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Springer Polyploidization and Cancer - Advances in Biology 676

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Description

Maintaining genome stability depends on limiting genome replication to once per cell cycle. While polyploidization serves a physiological role in certain specialized cell types, inappropriate polyploidization is linked to aneuploidy and transformation. This scientific text explores how surveillance mechanisms that prevent polyploidization are often disrupted in various cancers. As research evolves, new principles regarding genome stability continue to emerge. This volume from the Advances in Experimental Medicine and Biology series brings together leading experts in the field to provide a comprehensive overview of these complex biological processes. It serves as a vital resource for understanding the relationship between cell cycle regulation and cancer progression.

Key Features

Explores the relationship between genome replication limits and genome stability.

Examines how inappropriate polyploidization contributes to aneuploidy and transformation.

Analyzes the ways surveillance mechanisms are perturbed in cancer cells.

Provides insights into the underlying principles that maintain genome stability.

Features contributions from leaders in the field of experimental medicine and biology.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
21 May 2010
Listed Since
26 February 2010

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