Springer - Molecular Biology and Physiology of Water Transport

Explore the foundational science behind membrane permeability with this specialized text from Springer. This work covers the historical development of biophysical studies from the 1950s and 1960s that led to the understanding of water transporting proteins. It details the landmark discovery of CHIP28, the first molecular membrane water channel, which was later identified as aquaporin-1 (AQP1). This book provides a deep look into the integral membrane proteins found in erythrocyte membranes and various epithelial cells. By examining the relationship between water channels and aquaporins, readers gain insight into how these proteins function within biological systems. It serves as a comprehensive resource for understanding the molecular mechanisms that govern how water and solutes move across cell membranes.