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Springer Lipids in Protein Misfolding - Advances in Experimental Medicine Biology 855

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Description

This comprehensive volume from Springer examines the critical role of lipids in protein misfolding, a process underlying over 20 human diseases and representing a major public health challenge. Protein misfolding occurs when water-soluble native proteins convert into insoluble aggregates and fibrils that deposit as amyloid plaques, often involving errors in protein topology and lipid membrane assembly. Lipids are present in nearly all amyloid deposits in vivo and significantly influence protein misfolding mechanisms both in vitro and in vivo through multiple pathways. This book presents recent advances in understanding how lipids interact with misfolded proteins, offering essential insights for researchers, medical practitioners, and students studying neurodegenerative diseases, protein biochemistry, and lipid biology. Part of the established Advances in Experimental Medicine and Biology series, this volume provides evidence-based research and contemporary perspectives on protein aggregation disorders.

Key Features

Focuses on the role of lipids in protein misfolding mechanisms across over 20 human diseases associated with amyloid deposits.

Explores how water-soluble proteins convert to insoluble aggregates and fibrils that form amyloid plaques in biological systems.

Examines lipid influences on protein misfolding in both in vitro laboratory conditions and in vivo biological environments.

Part of the Advances in Experimental Medicine and Biology series, volume 855, published by Springer for medical and scientific professionals.

Addresses errors in protein topology and assembly in lipid membranes as contributing factors to protein conversion disorders.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
15 October 2016
Listed Since
07 October 2016

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