£114.66

Springer HSF1 and Molecular Chaperones in Biology and Cancer (1243)

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Description

Protein homeostasis, or proteostasis, forms the foundation of human health and disease management. This comprehensive volume explores how cells fold polypeptide chains into functional proteins, regulate intracellular signalling pathways, and coordinate tissue-wide communication through secreted signals. The proteostasis network maintains cellular health and physiological fitness, yet cancer cells exploit these same mechanisms to fuel tumour growth and metastasis. Written by world-leading experts, this book examines heat shock factor 1 (HSF1) and molecular chaperones across multiple biological contexts, bridging fundamental cell biology with cancer research. Part of Springer's Advances in Experimental Medicine and Biology series (volume 1243), it provides researchers, oncologists, and advanced students with current insights into how proteostasis dysfunction contributes to malignancy and how targeting these pathways may offer therapeutic opportunities.

Key Features

Part of the Advances in Experimental Medicine and Biology series (volume 1243) from Springer, offering peer-reviewed research on proteostasis and cancer.

Authored by world experts who explore HSF1 and molecular chaperone biology across cellular, tissue and organism-level contexts.

Covers the proteostasis network's role in both normal cell health and cancer cell survival, growth and tumour spread.

Addresses protein folding, intracellular signalling regulation and secreted signals that coordinate cells throughout the body.

Combines fundamental molecular biology with applied oncology research, suitable for researchers, clinicians and graduate-level students.

Examines how cancer cells hijack proteostasis mechanisms and potential therapeutic strategies targeting these pathways.

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