£131.92

Springer - DNA Methylation, Epigenetics and Metastasis Book

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Description

Explore the complex biological mechanisms behind cancer progression in this specialized volume from Springer. This text addresses the primary reason for cancer mortality: the ability of tumoral cells to detach from their original site, invade tissues, and disseminate through the bloodstream to distal locations. Once these transformed cells reach new sites, they begin to proliferate and cause further destruction. Over the last decade, research has identified several key genes that drive these processes. This book examines the roles of cadherins, laminins, heparan sulfates, and inhibitors of proteases and angiogenesis. By focusing on the relationship between DNA methylation, epigenetics, and the metastatic process, this work provides a deep look into why genetic alterations in these specific genes are often difficult to describe in human tumors despite their clear involvement in disease spread. This is a necessary resource for those studying cancer biology and the mechanisms of tumor dissemination.

Key Features

Examines the biological processes that allow tumoral cells to detach from original sites and invade the bloodstream.

Covers the role of specific genes such as cadherins, laminins, and heparan sulfates in cancer progression.

Provides research insights into inhibitors of proteases and angiogenesis within the context of metastasis.

Analyzes the relationship between DNA methylation and epigenetic changes in cancer cells.

Investigates the challenges of identifying genetic alterations in human tumors during the metastatic process.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
09 June 2005
Listed Since
30 December 2006

Barcode

No barcode data available

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