Springer - Biomedical Aspects of Drug Targeting - Book

Drug delivery faces significant challenges because most medications lack a natural affinity for the specific cells, tissues, or organs required for therapeutic success. This lack of precision often leads to low efficiency and unwanted side effects. These issues are especially serious when working with highly potent or cytotoxic anticancer drugs, enzymes, and genetic materials. For these agents to work safely and effectively, they require precise addressing at the cellular or sub-cellular level within the target organ. This book explores the necessary methods to meet safety, efficiency, and specificity requirements. It addresses the fundamental need for drugs to be targeted to the exact sites of their expected therapeutic action. By examining the biomedical aspects of targeting, this text provides insight into how to overcome the limitations of traditional drug administration and move toward more precise medical applications.