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Springer - Advancing Adverse Outcome Pathways Book

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Description

As social pressure to minimize animal testing grows and concerns regarding animal welfare increase, the scientific community faces a pressing need for more human-relevant and predictive toxicity tests. This Springer publication addresses these challenges by exploring new approaches to chemical screening through a systems biology lens. The text focuses on the Adverse Outcome Pathway (AOP), an analytical construct designed to describe a sequential chain of causally linked events. These events occur at different levels of biological organization and ultimately lead to adverse health or ecotoxicological effects. By moving beyond traditional toxicological pathway-based visions for human and ecological health assessment, this book provides a modern framework for understanding how chemical exposures result in biological consequences. It is an essential resource for researchers and practitioners looking to implement advanced methodologies in risk assessment and chemical safety testing.

Key Features

Explores the Adverse Outcome Pathway (AOP) as an analytical construct for understanding biological responses.

Provides a framework for describing sequential, causally linked events across different levels of biological organization.

Addresses the modern need for more human-relevant and predictive toxicity testing methods.

Offers insights into new approaches for chemical screening driven by animal welfare concerns.

Supports advancements in risk assessment for both human health and ecological safety.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
08 March 2018
Listed Since
12 July 2017

Barcode

No barcode data available

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