Humana Tumor Models in Cancer Research - Drug Discovery Book

Explore the latest advancements in cancer drug discovery and development with this comprehensive resource from Humana. Since the first edition, the field has seen significant progress in the development of genetically engineered mouse (GEM) models. These models are playing an increasingly important role in helping researchers understand the biology of malignant disease. This book tracks the evolution of GEM models as they move toward routine use in screening for new therapeutics. You will find information on the growing availability of genetically engineered mice, including those with conditional activation of oncogenes and models with multiple genetic changes. These advancements are bringing mouse models closer to representing human disease more accurately. This text is an essential update for those working in oncology research and therapeutic development.