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Humana Recombinant Antibodies Cancer Therapy Methods Protocols

Amazon

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£56.79 £50.78 £52.09 £53.40 £54.72 £56.03 £57.34 25 July 2026 12 August 2026 30 August 2026 17 September 2026 06 October 2026
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Description

This comprehensive guide explores recombinant antibody technology for cancer therapy, addressing the clinical limitations of traditional hybridoma-derived antibodies. Since hybridoma technology emerged over two decades ago, antibodies have become potent therapeutic agents in clinical settings, yet their repeated human application faces significant challenges from human antimouse antibodies (HAMA) development, which triggers allergic reactions and rapid neutralization of foreign murine proteins. Recombinant antibody methods overcome these obstacles through tailored molecular engineering approaches. This Methods in Molecular Biology volume 207 provides essential protocols and techniques for developing and optimizing recombinant antibodies, supported by promising initial clinical data demonstrating their therapeutic potential. Ideal for researchers, oncologists, and molecular biologists working in cancer immunotherapy, this reference combines theoretical foundations with practical laboratory methods for advancing antibody-based cancer treatments.

Key Features

Volume 207 in the Methods in Molecular Biology series focuses specifically on recombinant antibody development and cancer therapy applications.

Published by Humana Press Inc., this book delivers peer-reviewed protocols for generating and characterizing recombinant antibodies in clinical research.

Addresses the key limitation of human antimouse antibodies (HAMA) that reduces efficacy of traditional hybridoma-derived therapeutic antibodies.

Includes practical methods for tailoring recombinant antibodies to improve human tolerability and extend therapeutic effectiveness in cancer patients.

Combines decades of hybridoma technology knowledge with modern recombinant DNA approaches for enhanced immunotherapy strategies.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
16 September 2002
Listed Since
28 December 2006

Barcode

No barcode data available

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