Humana Recombinant Antibodies for Cancer Therapy - Volume 207

Explore the advancement of therapeutic agents in Recombinant Antibodies for Cancer Therapy: Methods and Protocols. This volume, part of the Methods in Molecular Biology series, addresses the evolution of antibody technology in clinical settings. While hybridoma technology introduced many potent agents, their use in humans often faced challenges like the development of human antimouse antibodies (HAMA), which can cause allergic reactions and rapid neutralization of the protein. This text examines how recombinant antibody technology provides a way to circumvent these limitations. By tailoring new antibodies through recombinant methods, researchers can move past the constraints of foreign murine proteins. The book covers the potential of these new therapies, supported by initial clinical data that shows encouraging results. It serves as a technical resource for understanding how recombinant methods are shaping the future of oncology and therapeutic antibody development.