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Humana PI3K-mTOR in Cancer and Cancer Therapy - Drug Discovery

Amazon

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£108.03 £107.58 £107.68 £107.78 £107.87 £107.97 £108.07 25 July 2026 12 August 2026 30 August 2026 17 September 2026 06 October 2026
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Description

This comprehensive guide explores the PI3K-mTOR pathway, one of the most frequently dysregulated signal transduction pathways in cancer biology. Written within the post-genome era framework, the book bridges molecular pathology with practical drug discovery applications, examining how PI3K-mTOR activation occurs downstream of growth factor receptors and through alternative mechanisms across diverse cancer types. The text is designed for researchers and practitioners seeking to understand the genomic and proteomic foundations of cancer-specific molecular pathways that drive tumour development and progression. By connecting pathway biology to therapeutic targeting strategies, this Cancer Drug Discovery and Development volume provides essential knowledge for identifying and validating PI3K-mTOR as a critical target in modern oncology drug development and personalised cancer treatment approaches.

Key Features

Focuses on PI3K-mTOR pathway as a primary target in cancer drug discovery and development strategies.

Covers molecular pathology approaches that move beyond traditional histopathology-based tumour classification systems.

Examines PI3K-mTOR activation mechanisms through growth factor receptor signalling and alternative regulatory pathways.

Provides genomics and proteomics insights into signal transduction pathways dysregulated across various cancer types.

Part of the established Cancer Drug Discovery and Development series for oncology researchers and pharmaceutical professionals.

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