Humana Mass Spectrometry Data Analysis in Proteomics 367

Mass Spectrometry Data Analysis in Proteomics provides an in-depth guide to the theory and practice of analyzing raw mass spectrometry (MS) data. Because MS is a high throughput technique, researchers must focus on the complexities of data analysis to ensure accuracy in their findings. This volume serves as a practical resource by outlining the bioinformatics programs, algorithms, and databases currently available for MS data analysis. Readers will find detailed general guidelines for data analysis using prominent search engines such as Mascot, Xtandem, and VEMS. The text places specific attention on the ability to identify poor quality data and provides methods for optimizing search parameters. This book is designed to help proteomic researchers navigate the technical requirements of their field, making it a valuable addition to any scientific library focused on biochemistry and molecular biology.