Humana Fragile-X Syndrome: Methods and Protocols (Methods in Molecular Biology 1942)

This comprehensive volume from Humana Press presents the latest methodologies for investigating Fragile-X Syndrome (FXS) across multiple research domains. The book covers epigenetic monitoring at the FMR1 locus, modelling FXS using human pluripotent stem cells and mouse neural progenitors, and comparative analysis between mouse and human-based pre-clinical research models. It also addresses Fragile-X associated Tremor/Ataxia Syndrome (FXTAS). Written in the established Methods in Molecular Biology series format, each chapter provides topic introductions, comprehensive materials and reagents lists, and detailed step-by-step protocols enabling researchers to implement current techniques for FXS investigation. This resource is essential for neuroscientists, molecular biologists, and clinical researchers studying neurodevelopmental and neurological disorders.