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Humana Exon Skipping: Methods and Protocols 867 Book

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Description

Exon Skipping: Methods and Protocols (Methods in Molecular Biology, 867) offers a detailed guide for scientists working with advanced genetic analysis. As next generation sequencing techniques become more common, they allow for deeper analysis of exons and introns across multiple genes simultaneously. This capability helps identify mutations that can lead to exon skipping. This volume provides the necessary guidance to move from discovery to functional testing. It covers protocols for testing mutations with a limited set of methods, as well as the specific tools and target genes required for the intentional induction of exon skipping. The text addresses the full translational path, moving from in vitro splicing studies to in vivo tests in animal models. By providing an extensive set of protocols, this book serves as a comprehensive resource for researchers navigating the complexities of molecular biology and gene regulation.

Key Features

Covers next generation sequencing techniques for detailed analysis of exons and introns in multiple genes.

Provides protocols for identifying mutations that potentially lead to exon skipping.

Includes methods for functional testing of mutations using a limited set of protocols.

Details the tools and target genes required for the intentional induction of exon skipping.

Supports the translational path from in vitro splicing to in vivo testing in animal models.

Acts as a comprehensive guide for scientists studying molecular biology and gene expression.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
28 March 2012
Listed Since
24 November 2011

Barcode

No barcode data available

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