£104.18

Humana Computational Methods for GPCR Drug Discovery 1705

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Description

Explore the latest advancements in pharmaceutical research with Computational Methods for GPCR Drug Discovery: 1705. This volume from the Methods in Molecular Biology series provides a deep look into modern computational strategies used to advance GPCR drug discovery. It covers essential techniques including structure-based and ligand-based approaches, along with cheminformatics. Readers will find detailed chapters on applying these methods to solve complex drug discovery challenges. The content addresses receptor structure modelling, protein-water-ligand interactions, and binding kinetics. It also covers the free energy of binding and the interconversion between agonists and antagonists. This text is designed to help researchers navigate the deorphanization of GPCRs and the discovery of biased and allosteric modulators. Whether you are studying receptor function and dynamics or looking for ways to improve prediction accuracy, this book serves as a technical resource for understanding modern molecular biology methodologies.

Key Features

Covers modern computational strategies including structure and ligand-based approaches for GPCR research.

Provides technical guidance on receptor structure modelling and studying protein-water-ligand interactions.

Explains methods for predicting binding kinetics and the free energy of binding in drug discovery.

Includes detailed information on the interconversion between agonists and antagonists.

Addresses advanced topics such as GPCR deorphanization and the discovery of allosteric modulators.

Offers insights into receptor function, dynamics, and the identification of biased modulators.

Product Specifications

Brand
Humana
Format
hardcover
Domain
Amazon UK
Release Date
30 November 2017
Listed Since
10 August 2017

Barcode

No barcode data available

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