£135.76

Heme Oxygenase: Enzyme Products in Medicine

Biological Science

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Description

Heme oxygenase is a critical enzyme responsible for breaking down heme, the iron-containing oxygen-carrying component of red blood cells. This comprehensive volume examines how heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) catalyse the physiological degradation of heme, yielding carbon monoxide, iron, and biliverdin IXalpha in the process. The book explores the elegant orchestration of these products and their roles in maintaining cellular homeostasis through oxygen sensing and utilisation. Particular focus is given to heme oxygenase-1, which demonstrates potent anti-inflammatory, anti-oxidant and anti-proliferative effects whilst being up-regulated by multiple physiological stimuli. This scientific text is essential for researchers, medical professionals and students seeking to understand the biochemical mechanisms underlying heme metabolism and its therapeutic implications in medicine.

Key Features

Focuses on heme oxygenase-1 (HO-1) and its potent anti-inflammatory, anti-oxidant and anti-proliferative properties in cellular biology.

Details the physiological degradation process catalysed by functional isozymes that produce carbon monoxide, iron, and biliverdin IXalpha.

Examines how heme oxygenase maintains cellular homeostasis through oxygen sensing and utilisation mechanisms.

Covers the up-regulation of heme oxygenase by multiple stimuli relevant to medical and therapeutic applications.

Published by Nova Science Publishers Inc for academic and professional reference in biological sciences.

Product Specifications

Format: hardcover
ASIN: 1594544476
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 06 June 2005
Listed Since: 13 December 2006

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Heme Oxygenase: Enzyme Products in Medicine

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