Genotoxicity: Evaluation, Testing and Prediction - Genetics Research

This comprehensive book examines genotoxicity, the deleterious action on cell genetic material that affects its integrity and stability. Genotoxic substances are potentially mutagenic or carcinogenic, capable of causing genetic mutations and contributing to tumour development. In humans, DNA damage or genotoxicity may result from exposure to external agents including radiation, pesticides, hydrocarbon combustion products, and antineoplastic drugs, as well as internal factors driven mainly by excessive free radical production from certain diseases. This research text provides essential evaluation methods, testing protocols, and prediction strategies for understanding and assessing genotoxic risks in biological systems and human health contexts.