£170.39

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Cycloaddition Reactions: Advances in Research and Applications

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Description

Explore the latest developments in organic chemistry with Cycloaddition Reactions: Advances in Research and Applications. This specialized text from the Chemistry Research and Applications series provides a detailed look at recent progress in aryne cycloaddition reactions. Chapter 1 focuses on the methodology for preparing arynes under mild reaction conditions, specifically highlighting the in-situ generation of arynes through the reaction of ortho-OTMS aryl triflates with fluoride ions. This highly applicable method enables the use of various arynophiles to synthesize nitrogen and oxygen containing 5-7 membered heterocycles. The book also provides instructive examples of these applications in the total synthesis of natural products, including radermachol, (+/-)-tylophorine, calothrixins, tubingensin B, and (+)-hinckd. This resource is an essential addition for researchers and students studying organic synthesis and complex molecular structures.

Key Features

Provides a detailed review of recent progress in aryne cycloaddition reactions within the field of organic chemistry.

Covers important methodologies for the preparation of arynes using mild reaction conditions.

Explains the in-situ generation of arynes via the reaction of ortho-OTMS aryl triflates with fluoride ions.

Describes the synthesis of nitrogen and oxygen containing 5-7 membered heterocycles using various arynophiles.

Includes instructive examples of total synthesis for natural products like radermachol and (+/-)-tylophorine.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
11 May 2019
Listed Since
05 March 2019

Barcode

No barcode data available

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