CRC Press - Uveal Melanoma: A Model for Cancer Biology

Uveal melanoma stands as the most frequent intraocular malignancy found in adults. While the factors that predispose patients to this disease remain largely unknown, recent scientific advancements have provided new ways to study its development. This book explores how the availability of specific uveal melanoma cell lines has enabled novel in vitro and in vivo studies. Through these research methods, scientists have expanded our understanding of the immunology, genetics, and molecular biology associated with the disease. One of the most significant findings discussed is the distinction between uveal melanoma and cutaneous melanoma, which are remarkably different diseases. This text summarizes recent developments regarding the biology and metastasis of uveal melanoma, providing a comprehensive look at current research in the field. It serves as a specialized resource for professionals and researchers looking to understand the unique biological profile of this specific cancer.