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CRC Press JAK-STAT Signaling in Diseases - CRC Press Medical Reference

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Description

JAK-STAT Signaling in Diseases by CRC Press is a comprehensive medical reference exploring one of the body's most important signal transduction pathways. This authoritative guide examines how the JAK-STAT pathway regulates critical biological processes including cell differentiation, proliferation, cell death, hematopoiesis and immune responses. Written for medical practitioners and healthcare professionals, the book explains how this elegant and evolutionarily conserved pathway responds to growth factors and cytokines to control gene expression at the nuclear level. It investigates the role of JAK-STAT mutations and polymorphisms in the development and progression of inflammatory diseases, making it an essential resource for understanding immunological disorders and their molecular mechanisms. Ideal for internal medicine specialists, immunologists and clinical researchers seeking deep insight into pathological signalling cascades.

Key Features

JAK-STAT Signaling in Diseases covers cell differentiation, proliferation and cell death regulation through the JAK-STAT pathway mechanism.

Published by CRC Press, this medical reference addresses hematopoiesis and immune response processes controlled by JAK-STAT signalling.

The book examines how growth factors and cytokines activate the JAK-STAT cascade to regulate transcription of genes at the nucleus.

Explores JAK-STAT mutations and polymorphisms associated with inflammatory diseases and their clinical implications for practitioners.

Designed for internal medicine specialists, immunologists and healthcare professionals studying signal transduction pathways in disease.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
12 March 2020
Listed Since
19 September 2019

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