£121.78

CRC Press - JAK-STAT Signaling in Diseases - Medical Text

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Description

Explore the fundamental mechanics of the JAK-STAT signaling pathway with this specialized medical resource from CRC Press. This text examines how this signal transduction pathway manages multiple homeostatic biological processes, including cell differentiation, proliferation, and cell death. As an evolutionary conserved pathway, JAK-STAT provides an elegant mechanism for regulating gene expression via external parameters. This book covers how the cascade, activated by cytokines or growth factors, regulates gene transcription at the nucleus. It also addresses the clinical implications of the pathway, specifically how mutations and polymorphisms in JAK-STAT are associated with inflammatory conditions. This is a necessary resource for professionals studying immunology, hematopoiesis, and immune responses.

Key Features

Detailed analysis of the JAK-STAT pathway and its role in regulating gene expression at the nucleus.

Covers essential biological processes including cell differentiation, proliferation, and cell death.

Examines the impact of mutations and polymorphisms in the pathway on inflammatory conditions.

Provides insight into how growth factors and cytokines activate this signal transduction cascade.

Explores the pathway's role in hematopoiesis and various immune responses.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
12 March 2020
Listed Since
19 September 2019

Barcode

No barcode data available

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