CRC Press Dose Optimization in Drug Development - CRC Press

This reference provides a concise overview of key principles in dose selection and optimization, demonstrating applicability to recent successful new drug applications. Compiling essential issues and current research on safety, efficacy, clinical pharmacology, and PK-PD relationships, the volume critically examines the multidisciplinary nature of drug development. Spanning pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine, this book serves as a comprehensive resource for professionals involved in pharmaceutical research and development who need to understand dose optimisation strategies and their practical implementation in bringing new drugs to market.