Elsevier Human Mitochondrial Genome: Biology to Disease - Elsevier

The Human Mitochondrial Genome: From Basic Biology to Disease provides a thorough, current exploration of human mitochondrial genomics, bridging fundamental research with practical medical applications across diverse disease contexts. Written by international specialists, this comprehensive resource examines the core biology of human mitochondrial DNA (mtDNA), covering its upkeep, restoration, cellular distribution, and inheritance patterns. The book investigates mtDNA evolution and utilisation, genetic variations, experimental techniques, and research models for studying mtDNA function in detail. Disease chapters include clinical insights and therapeutic approaches, making it an essential reference for researchers, clinicians, and students seeking to understand mitochondrial dysfunction and its role in human health and disease.