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Elsevier RNA-Ligand Interactions Part A - Structural Biology Methods

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Description

RNA-Ligand Interactions, Part A is a comprehensive guide to structural biology methods for studying RNA interactions, part of the Methods in Enzymology series Volume 317. This established laboratory reference covers semisynthetic methodologies including RNA synthetic methods and RNA derivatization techniques, alongside advanced RNA structure determination approaches using X-ray crystallography, NMR spectroscopy, and electron microscopy. The volume presents techniques for monitoring RNA conformation and dynamics through solution methods, electrophoretic analysis, and spectroscopic approaches, plus methods for modeling tertiary structure. As a critically acclaimed laboratory standard trusted for over forty years, Methods in Enzymology provides researchers and biochemists with practical, peer-reviewed protocols and detailed methodologies essential for advanced RNA research and molecular interaction studies.

Key Features

RNA-Ligand Interactions Part A covers semisynthetic RNA methodologies, including synthetic methods and derivatization protocols for chemical modification.

Volume 317 presents three main structural determination techniques: X-ray crystallography, NMR spectroscopy, and electron microscopy for RNA analysis.

The Methods in Enzymology series provides established laboratory protocols for monitoring RNA conformation changes and dynamic behaviour using solution and spectroscopic methods.

Includes modelling approaches for tertiary structure prediction, essential for understanding complex RNA-ligand binding mechanisms.

Academic Press publication represents forty years of laboratory-tested protocols trusted by biochemistry researchers and structural biologists worldwide.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
03 June 2000
Listed Since
06 February 2007

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