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Elsevier Genome Plasticity in Health and Disease - Translational Genomics

Amazon

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Price range: £122 - £135

Price levels: 2 different prices over 64 days

Description

Genome Plasticity in Health and Disease delivers a comprehensive, current exploration of how genome plasticity shapes human physiology and contributes to disease development. This translational and applied genomics resource covers genomic and epigenomic analysis techniques, model organism applications, and genomic database utilisation in research. The book examines specific molecular and biochemical mechanisms underpinning genome plasticity, including somatic variants, de novo variants, founder variations, isolated population dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, and transcription factors. Published by Academic Press, this reference bridges fundamental genomic concepts with practical clinical applications for researchers, clinicians, and students seeking deeper understanding of how genomic flexibility influences both health and disease states.

Key Features

Covers genomic and epigenomic analysis methods essential for understanding genome plasticity mechanisms and their clinical relevance.

Examines somatic variants, de novo variants, and copy-number variations with detailed molecular mechanisms and disease implications.

Integrates model organism research and genomic databases to provide comparative insights into genome plasticity across species.

Discusses DNA methylation, histone modifications, and transcription factors as epigenetic drivers of genomic plasticity.

Explores founder variations and isolated population dynamics to explain how genetic drift affects genome stability and disease susceptibility.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
24 April 2020
Listed Since
01 October 2019

Barcode

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