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Elsevier Enzymes of Polyamine Metabolism Volume 715 - Methods in Enzymology

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£137.99 £119.51 £123.54 £127.57 £131.61 £135.64 £139.67 30 July 2026 15 August 2026 01 September 2026 18 September 2026 05 October 2026
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Description

Enzymes of Polyamine Metabolism: Volume 715 presents cutting-edge research on polyamine metabolic pathways and enzymatic regulation. This Methods in Enzymology volume explores the convergence of MYC signalling and hypusine circuits in metabolic control, advanced structural and enzymatic analysis of HDAC10, and innovative TR-FRET assay methodologies for profiling HDAC10 inhibitors and PROTACs. The book examines polyamine transport inhibitors with detailed methods for measuring polyamine uptake in mammalian cellular systems, alongside comprehensive evaluation of platinum drug toxicity mechanisms arising from polyamine catabolism. Additional chapters address acrolein adducts generated during polyamine breakdown and alterations in polyamine metabolism. Published by Academic Press, this volume serves researchers, biochemists, and molecular biologists seeking detailed experimental protocols and current advances in understanding polyamine enzyme systems and their metabolic regulation.

Key Features

Volume 715 of Methods in Enzymology series covers MYC and hypusine circuit convergence in metabolic control mechanisms.

Detailed HDAC10 structural analysis and enzymatic characterisation with TR-FRET assay methods for inhibitor and PROTAC profiling.

Comprehensive methods for polyamine transport inhibitors and protocols for measuring polyamine uptake in mammalian cells.

Evaluation of platinum drug toxicity resulting from polyamine catabolism and acrolein adduct measurement techniques.

Academic Press publication providing current research on polyamine metabolism alterations and enzymatic regulation.

Experimental protocols and methodologies designed for biochemists and molecular biology researchers studying polyamine pathways.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
01 June 2025
Listed Since
04 December 2024

Barcode

No barcode data available

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