£131.66

Academic Press Advanced Methodologies to Study Cellular Cytotoxicity Against Cancer - Volume 207

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Description

Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 is a comprehensive scientific resource from Academic Press that explores cutting-edge techniques for investigating and boosting cytotoxic activity in cells targeting cancer. This volume covers essential protocols and methodologies including ex vivo assays to assess CAR T cell cytotoxicity in viable tumour tissues using two-step staining protocols, new methods to measure mitochondria polarisation and function at the immunological synapse, and analysis of CAR-T cell-mediated cytotoxicity in solid tumour models. The book addresses investigation of in vitro lytic capacity of CAR-T cells through microscopy and related approaches. Designed for researchers, oncologists and laboratory professionals, this Methods in Cell Biology volume provides practical strategies and detailed protocols to advance cancer immunotherapy research and enhance understanding of cellular cytotoxic mechanisms.

Key Features

Volume 207 includes ex vivo assays for assessing CAR T cell cytotoxicity in viable tumour tissues using advanced two-step staining protocols.

New protocols presented in this volume measure mitochondria polarisation and function specifically at the immunological synapse.

Analysis methods for CAR-T cell-mediated cytotoxicity in solid tumour models are detailed throughout this Methods in Cell Biology resource.

Investigation techniques for in vitro lytic capacity of CAR-T cells using microscopy and related analytical approaches are included.

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