Textbook Of Inflammatory Diseases: Mechanisms, Immunopathology, and Clinical Management of Acute and Chronic Inflammatory Conditions

When inflammation appears in the joints, skin, kidneys, lungs, vessels, nervous system, or blood, how do you connect the biology to the bedside? Textbook of Inflammatory Diseases gives you a structured, clinically oriented path through the science and practice of immune-mediated illness. Across 20 chapters, Irene M. Kovac moves from foundational inflammatory biology to organ-specific disorders, diagnostic evaluation, and pharmacologic decision-making, helping you understand not only what happens in the body, but why it matters for patient care. This medical reference is built for readers who need a serious, organized guide to inflammation across specialties. You will study innate and adaptive immunity, inflammasomes, cytokine networks, fibrosis, autoinflammatory syndromes, rheumatoid arthritis, spondyloarthritis, lupus, vasculitis, mucosal disease, allergy, dermatology, renal disease, neuroinflammation, cardiometabolic inflammation, sepsis-associated dysregulation, biomarkers, imaging, histopathology, biologics, targeted small molecules, and long-term monitoring. Inside this book, you'll discover: Master the cellular and vascular events that shape inflammation, edema, pain, fever, tissue injury, repair, and failed resolution. Build stronger diagnostic reasoning by linking symptoms, laboratory markers, imaging patterns, tissue findings, and disease activity over time. Recognize major autoimmune and autoinflammatory patterns, including lupus, vasculitis, rheumatoid arthritis, recurrent fever syndromes, and crystal-associated syndromes. Understand organ-specific inflammation in the skin, kidney, nervous system, eye, airways, gut, cardiovascular system, and metabolic tissues. Navigate immunomodulatory therapy with clearer attention to corticosteroids, conventional agents, biologics, JAK inhibitors, safety screening, infection risk, vaccination, and monitoring. Apply integrated care principles for remission, relapse prevention, comorbidities, pregnancy considerations, frailty, adherence, and multidisciplinary coordination. Whether you are studying medicine, revising advanced pathology, supporting specialty training, or strengthening your clinical framework, this book helps you approach inflammation as a connected system. It also gives you appendices, safety tables, care checklists, a glossary, and a bibliography to support focused review after each major topic. Ready to make complex inflammatory disease easier to organize? Begin with a framework that connects immune biology, organ damage, diagnosis, therapy, and long-term care.