Modern Blood Banking and Transfusion Practices: The Complete Immunohematology and Transfusion Medicine Textbook for MLS, SBB, and Clinical Practice ... Patient Blood Management, Transfusion Safety

Every transfusion is a chain of decisions that begins in the laboratory and ends at the bedside. A unit is screened. An antibody is identified. A crossmatch is resolved. A component is selected, issued, and infused, and someone watches for the reaction that must not be missed. This textbook follows that chain from end to end, written for the people who hold each link, and it reinforces every stage with review questions at the close of each chapter to turn reading into retained knowledge. It is a single resource that spans the full discipline, deep enough to teach the student meeting blood group systems for the first time and current enough to serve the technologist, the blood banking specialist, and the physician already in practice. What the book covers: Scientific foundations: red blood cell and platelet preservation and storage lesion science, the medical genetics behind blood banking, the immunology of transfusion including antibody structure and complement, and molecular diagnostics from PCR through next-generation sequencing, microarray genotyping, and CRISPR. The serologic core: the antiglobulin test and its troubleshooting, the ABO and Rh systems, the major systems including Lewis, P1PK, I, MNS, Kell, Duffy, Kidd, and Lutheran, the uncommon and newly recognized systems, antibody detection and complex problem solving, and pretransfusion compatibility testing. Technology and molecular practice: blood bank testing automation and AI-assisted laboratory operations, and the clinical use of genotyping to resolve serologic problems. The blood supply: donor selection, screening, and recruitment, transfusion-transmitted disease testing and NAT technologies, component preparation and quality standards, and cord blood and stem cell collection through cryopreservation. Transfusion practice: component selection and clinical decision algorithms, adverse effects of transfusion and their management, massive transfusion and damage control resuscitation, apheresis and extracorporeal photopheresis, and cellular therapy in the transplant setting including CAR-T and gene therapy. Clinical transfusion medicine: hemolytic disease of the fetus and newborn, the autoimmune hemolytic anemias, transfusion in sickle cell disease and thalassemia, transfusion in special populations from neonates to oncology and transplant recipients, and the HLA system in transplantation and transfusion. Systems, safety, and the future: relationship and forensic testing, quality management systems, patient blood management as a hospital-wide strategy, haemovigilance and patient safety culture, the FDA, AABB, CAP, and TJC regulatory frameworks, laboratory information systems and data analytics, medicolegal and ethical aspects, and the future of the field under global transfusion medicine and artificial intelligence. Who it is for: Medical laboratory science students learning immunohematology in depth. Specialist in Blood Banking (SBB) candidates and certification examinees. Practicing technologists and laboratory scientists at the bench. Transfusion medicine physicians, residents, and patient blood management teams. The book keeps to one thing throughout: to connect what happens in the tube to what happens to the patient. Each chapter builds from principle to application and ends with review questions that consolidate the material, while reference appendices gather the data, values, and quick-reference tables that matter most when time is short. From the storage lesion to the sequencing run, from an ABO discrepancy to a hospital-wide patient blood management program, this book traces the blood from donor to recipient and back to the laboratory that keeps the transfusion safe. It is built to be read cover to cover as a course text and kept on the bench as a working reference long after.