Endocrinology Diagnosis & Treatment Handbook: A Clinical Textbook Covering Pituitary, Thyroid, and Adrenal Disorders for Internal Medicine Residents

The new patient with acanthosis nigricans, an HbA1c of 11.4, an LDL of 218, a BMI of 36, episodic palpitations, and a father who died of sudden cardiac death at 47 is sitting in your exam room — and you have eighteen minutes to build a plan that addresses every one of those threads. When endocrine and metabolic problems are managed in isolation rather than as the integrated cardiorenal-metabolic syndrome they have become, patients accumulate years of inadequately controlled disease, preventable cardiovascular events, missed familial cancer syndromes, and the iatrogenic complications of regimens that no longer reflect contemporary evidence. This is the working framework that lets you reason from mechanism to bedside decision across every endocrine and metabolic presentation in adult medicine. Inside this book: • Mechanism-based reasoning — work from pathophysiology to management decision in real clinical time, across pituitary, thyroid, adrenal, parathyroid, gonadal, and pancreatic disease • Cardiorenal-metabolic integration — apply the SGLT2 inhibitor and GLP-1 receptor agonist evidence base across diabetes, heart failure, and chronic kidney disease in a single coherent strategy • Acute hyperglycemic emergencies — manage DKA and HHS to anion gap closure and osmolar correction with the protocol-level detail the bedside requires • Endocrine hypertension recognition — identify the 5–15% of hypertensive patients with primary aldosteronism, pheochromocytoma, Cushing syndrome, or renovascular disease using ARR, metanephrines, and the 1 mg DST • MEN syndrome cascade testing — convert an index diagnosis into surveillance and prophylactic intervention across an entire family • Contemporary obesity pharmacotherapy — apply semaglutide, tirzepatide, and the SELECT trial evidence to weight, glycemia, and cardiovascular risk reduction • Pregnancy endocrinology — adapt thyroid, adrenal, glucose, and pituitary management across the gestational and postpartum periods For internal medicine residents, hospitalists, primary care physicians, nurse practitioners, physician assistants, pharmacists, fellows, and medical students transitioning into clinical years. Open the book. The next patient deserves the framework.