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Treatise on Biophotonic Orthoinfectology: Modulation of the Osteoarticular Infectious Microenvironment with Nanotechnology, Smart Implants, and Light-Based Therapies

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Description

Treatise on Biophotonic Orthoinfectology presents an integrative scientific framework for understanding osteoarticular infections as complex microenvironmental phenomena involving dynamic interactions between microorganisms, host tissues, biomaterials, and physical-energetic factors. This work explores the convergence of bioengineering, photonics, nanotechnology, and clinical science to analyze how controlled physical stimuli and advanced materials may influence infectious microenvironments under experimental and translational perspectives. The book examines biological foundations of osteoarticular infections, biofilm persistence, host immune responses, and tissue regeneration, integrating these elements with principles of light–tissue interaction, plasmonics, nanomaterials, photodynamic mechanisms, photothermal effects, and smart implant technologies. Emerging diagnostic and monitoring strategies, including biosensors and microenvironmental assessment methods, are also discussed within a multidisciplinary framework. Clinical contexts such as osteomyelitis, periprosthetic infections, post-traumatic infections, spinal infections, and implant-associated complications are analyzed from a microenvironmental perspective, emphasizing scientific limitations, biological safety, and technological barriers. Ethical, regulatory, and translational considerations are addressed to support responsible scientific development. Rather than proposing replacement of established therapies, this treatise aims to expand scientific understanding by integrating biological, physical, and engineering principles, contributing to future research directions in musculoskeletal infection science. This book is intended for physicians, orthopedic specialists, infectious disease professionals, biomedical engineers, researchers, and graduate students interested in emerging interdisciplinary approaches to complex infections.

Product Specifications

Format
hardcover
Domain
Amazon UK
Release Date
01 March 2026
Listed Since
02 March 2026

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