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Price distribution over 68 days • 1 price levels

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Price Analysis

Most common price: £72 (68 days, 100.0%)

Price range: £72 - £72

Price levels: 1 different prices over 68 days

Description

Peripheral nerve disorders represent one of the most prevalent and clinically complex categories of neurological disease worldwide. From metabolic and autoimmune neuropathies to hereditary demyelinating syndromes and toxic axonopathies, degeneration of peripheral nerves presents with diverse mechanisms, variable progression, and profound functional consequences. A rigorous understanding of the biological, molecular, and clinical foundations of peripheral nerve injury is essential for modern neurological practice. This comprehensive textbook provides an integrated, evidence-based exploration of peripheral nerve degeneration, bridging foundational neurobiology with clinical neurology and translational therapeutics. Beginning with detailed discussions of peripheral nerve anatomy, Schwann cell biology, axonal transport, and myelin architecture, the text establishes a strong scientific framework before progressing into the molecular mechanisms that underlie demyelination, axonal injury, oxidative stress, mitochondrial dysfunction, and neuroinflammation. The book offers in-depth analysis of immune-mediated neuropathies, metabolic and toxic neuropathies, hereditary demyelinating conditions, and small fiber and autonomic disorders. Each major disease category is contextualized within its pathophysiological mechanisms, emphasizing how molecular processes translate into clinical phenotypes. Diagnostic strategies—including electrophysiology, biomarker evaluation, imaging modalities, and histopathology—are presented with clarity and precision, allowing readers to connect bedside assessment with underlying biological mechanisms. Special attention is devoted to Schwann cell repair biology, mechanisms of remyelination and remyelination failure, and the transition from reversible demyelination to irreversible axonal loss. The text further examines emerging therapeutic strategies, including immunomodulation, neuroprotective agents, regenerative medicine approaches, gene-targeted therapies, and biomarker-driven precision medicine. Structured for advanced medical students, neurology residents, neuroscientists, and clinicians, this volume integrates structured headings, detailed tables, mechanism-based explanations, and clinically relevant synthesis. It emphasizes evidence-based reasoning and translational relevance, ensuring that readers gain both conceptual mastery and practical insight. By uniting molecular neuroscience with clinical neurology, this textbook serves as a definitive resource for understanding the mechanisms, manifestations, and management of peripheral nerve degeneration in contemporary medicine.

Product Specifications

Format: hardcover
ASIN: B0GNGDMSV2
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders > Oncology
Domain: Amazon UK
Release Date: 13 February 2026
Listed Since: 14 February 2026

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Peripheral Nerve Degeneration: Pathophysiology, Biomarkers, and Emerging Therapies

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