Springer Immunotherapy – A Novel Facet of Modern Therapeutics

This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs.  It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance.  Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.  From the Back Cover This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs.  It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance.  Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies.  About the Author Sujata P. Sawarkar is Professor and Head of Department, Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, India. Before joining academics Dr. Sujata Sawarkar was associated with major pharmaceutical companies in India at managerial position, in the field of Research and Development, formulation development of conventional and novel dosage forms for regulated and domestic market. Several oral solid dosage forms and sterile products developed by her team have received approval in US and EU and have been commercialized. She has about total 22 years of research and teaching experience. Her research interests include Formulation Development of novel drug delivery and targeted systems based on nanotechnology for oral, ophthalmic, colonic and vaginal delivery, development of evaluation techniques for novel drug delivery systems, Translational research. Dr. Sujata Sawarkar has been Executive Member of Controlled Release Society (India Chapter) since 2014 and Secretary of Controlled Release Society (India Chapter) CRS IC for 2017-2019. She has been invited reviewer for Indian Drugs, AAPS PharmSciTech, International Journal of Nanomedicine Dove Press, Drug Design, Development and Therapy, Journal of Bioequivalence & Bioavailability, European Journal of Pharmaceutics and Biopharmaceutics and Journal of Cosmetic Dermatology . Dr. Sujata Sawarkar has received research project grants worth about 85 lakhs rupees (8.5 million INR i.e. about 1.19 million USD) from Industry and Government funding agency. She has presented about 50 research papers in national and international conferences like CRS Inc. and AAPS. She has several papers published in peer reviewed journals like AAPS PharmSciTech, International Journal of Pharmaceutics, Critical Reviews in Therapeutic Drug Carrier systems, Drug Development and Translational Research, Frontiers in Pharmacology , Expert Opinion on Drug Delivery. She has coauthored 5 book chapte