£161.17

About as cheap as it gets — within 5% of the all-time low it hit 1 month ago.

£161 today · all-time low £159 (Sep 2026) · usually £159

Springer Aluminum and renal failure: 26 (Developments in Nephrology)

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£166.08 £158.41 £160.09 £161.76 £163.43 £165.10 £166.78 18 July 2026 08 August 2026 30 August 2026 20 September 2026 12 October 2026
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30 days 3 days · current 54 days 0 14 27 41 54 £159 £161 £166 Days at Price

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Most common price: £166 (54 days, 62.1%)

Price range: £159 - £166

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Description
Increasing the accumulation of aluminum in the bone (body) in cases of renal osteodystrophy may influence the histopathologic aspect of the bones. Alumi num blunts the effect of increased PTH secretion and favours the genesis of osteoid. That means, in cases of renal failure combined with aluminum accumulation, a relatively low bone tunover is found and no fibrosis of the bone marrow. Furthermore the amount of osteoid is increased. This means that there is evidence of osteomalacia especially when the latter is defined as an increased amount of osteoid covered with a relatively low number of cubic osteoblasts. To a certain extent the effect of aluminum accumulation is comparable to the effect of PTX. Treatment with DFO may normalize the bone, although not necessarily with a concomittant disappearance of alumi num from the bone. The presence of aluminum in the bone can be suggested by routine histologic investigation of the bone and can be made rather probably by the aluminum staining combined with iron-staining, but can only be proven by more advanced techniques like ET AAS and LAMMA. References 1. Boyce BF, Elder HY, Elliot HL, Fogelman I, Gell GS, lunor Bl, Beastall G, Boyle YT, 1982: Hypercaicaemic ostemalacia due to aluminium toxicity. Lancet 6: 1009. 2. Verbueken AH, Visser Wl, Van de Vyver FL, Van Grieken RE, De Broe ME, 1986: The use of laser microprobe mass analysis (LAMMA) to control the staining of aluminum by aurin tricarboxylate (aluminon). Stain Technology 61: 287.

Product Specifications
Brand
Springer
Format
paperback
ASIN
9401073333
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Renal
Domain
Amazon UK
Publication Date
19 October 2011
Listed Since
14 June 2013

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