Springer Stem Cells and Cancer Stem Cells, Volume 2: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 2

Product Description This book examines applications of stem cells and cancer stem cells in therapy for disease and organ/tissue injury. Coverage includes current methodologies of regenerative medicine and tissue engineering, tailored specificaly to numerous types of stem cells. Review From the reviews: “Stem cells and cancer stem cells are 2 distinct, evolving, and promising areas of research. … This book, the second in a planned series of 7 volumes, covers select new research in both fields. This book highlights selected research from renowned scientists around the world. … Stem Cells and Cancer Stem Cells would be most helpful for basic science researchers studying stem cells and for cancer stem cell preclinical research.” (Paulette Mehta, Journal of the American Medical Association, Vol. 307 (10), March, 2012) “This well-written book not only describes current laboratory techniques for studying stem cells, but also summarizes important aspects of the clinical potential of stem cell-based therapy in cancerous and noncancerous human diseases. … a much-needed update of the progress made in major areas of stem cell research applied to clinical medicine. … written for specialists and experts in different areas of clinical medicine, it is an excellent reference and guide for students and basic researchers with a particular interest in this promising and expanding field.” (Luigi Strizzi, Doody’s Review Service, March, 2012) From the Back Cover As in volume 1 of this series, this volume presents information on stem cells and cancer stem cells; Therapeutic Applications in disease and tissue/organ injury. Methodologies of regenerative medicine and tissue engineering are major components of this volume. Specific stem cells discussed are: human embryonic stem cells, hematopoietic stem cells, cord blood stem cells, human pluripotent stem cells, gliosarcoma stem cells, induced pluripotent stem cells, intestinal stem cells, human thyroid cancer stem cells, tumor stem cells, menstrual stem-like cells, neural stem cells, breast cancer stem cells, allogeneic mesenchymal stem cells, fetal membrane-derived mesemchynmal stem cells, and omental stem cells. The method for isolating bone marrow stromal cells is explained. Method for generating marmoset-induced pluripotent stem cells, using transcription factors, is also explained. Use of stem cell lines in therapeutic applications is discussed. Programming of stem cells is described. Methods for transplantation of stem cells are presented. Use of various types of stem cells for conditions such as stroke, ischemia, heart diseases, Alzhemier’s disease, and neurogenerative diseases in general, is explained. For example, generation of human cardiac muscle cells from adipose-derived stem cells is included. Another example is repairing bone defects using mesenchymal stem cells and mesenchymal-derived endothelial cells. Differentiation of new neurons from neural stem cells is described. Method for repairing retina condition using human embryonic stem cells is explained; these cells can induce neural differentiation. Treatment of graft-versus-host disease resulting from hematopoietic stem cell transplantation is elaborated.