Springer Tumors of the Central Nervous System, Volume 1: Gliomas: Glioblastoma (Part 1)

This book presents recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain. It examines the importance of personalized medicine and clinical validation for targeted therapy. Review From the reviews:“This is an outstanding book on every molecular mediator of cancer stem cells, angiogenesis, surface markers, and CAD mediators of oncogenesis in the brain. … This is a very good book for neuropathologists and neurosurgeons.” (Joseph J. Grenier, Amazon.com, June, 2014) From the Back Cover The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed.