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Molekulare Charakterisierung von Panton-Valentine-Leukocidin: und Exfoliatinetoxinen in lokalen Isolaten von Methicillin-resistentem Staphylococcus aureus

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£57.55 £54.67 £55.82 £56.97 £58.13 £59.28 £60.43 10 September 2026 13 September 2026 16 September 2026 19 September 2026 22 September 2026
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Description

MRSA weist mehrere Virulenzfaktoren auf, darunter Koagulase, Hyaluronidase, Alpha-Toxin, Superantigene, Protein A, Adhäsionsfaktoren (Adhäsine), Pigmente, Biofilmbildung und Toxine. Exfoliative Toxine (ET) sind epidermolytische Toxine, bei denen es sich um Serinproteasen handelt, die Desmosom-Cadherine nur in den oberflächlichen Hautschichten erkennen und spalten, was direkt für die klinische Manifestation des Staphylokokken-Hautsyndroms (SSSS) verantwortlich ist. Panton-Valentine-Leukozidin ist ein Zytotoxin - eines der β-Poren-bildenden Toxine. Das Vorhandensein von PVL ist mit einer erhöhten Virulenz bestimmter Stämme von Staphylococcus aureus verbunden. Es betrifft die Haut oder Schleimhaut, einschließlich nekrotischer hämorrhagischer Pneumonie. PVL bildet Poren in den Membranen infizierter Zellen. Das Ziel dieser Studie war es, die Prävalenz der pvl- und et-Gene unter lokalen Methicillin-resistenten Staphylococcus aureus-Isolaten zu bewerten und eine charakteristische Untersuchung des PVL-Toxins aus MRSA-Isolaten in Bagdader Krankenhäusern durchzuführen.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
14 October 2025
Listed Since
15 October 2025

Barcode

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