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ÉDITIONS UNIVERSITAIRES EUROPÉENNES Fragmentation de l'ADN spermatique par cytométrie en flux

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£52.00 £49.40 £50.44 £51.48 £52.52 £53.56 £54.60 21 July 2026 04 August 2026 18 August 2026 01 September 2026 16 September 2026
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Description

La fragmentation de l'ADN spermatique consiste à des cassures simples ou doubles brins dans le matériel génétique des spermatozoïdes. C'est une anomalie susceptible de réduire le pouvoir fécondant des spermatozoïdes. Elle constitue de ce fait une des étiologies de l'infertilité masculine.Ainsi, l'étude de la fragmentation de l'ADN spermatique trouve sa place dans le bilan d'exploration de l'infertilité masculine avec l'analyse du spermogramme d'une part, et dans le cadre des techniques de procréation médicalement assistées d'autre part. La technique de cytométrie en flux est l'une des approches utilisées en pratique clinique pour évaluer la fragmentation de l'ADN spermatique.D'autre part, une fragmentation accrue de l'ADN spermatique peut être associée à plusieurs facteurs extrinsèques (tels que l'exposition à la chaleur, le tabagisme, les infections urogénitales et la varicocèle) ou intrinsèques en rapport avec une maturation défectueuse des cellules germinales liées au stress oxydatif.Certains de ces facteurs peuvent être réversibles et/ou curables ce qui pourrait améliorer la qualité de l'ADN spermatique et le pronostic obstétrical du couple.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
18 July 2024
Listed Since
12 August 2024

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