Development of Mucoadhesive Buccal Patch of Timolol Maleate - Image 1

£53.00

LAP Lambert Academic Publishing Development of Mucoadhesive Buccal Patch of Timolol Maleate

Name: Development of Mucoadhesive Buccal Patch of Timolol Maleate
Brand: LAP Lambert Academic Publishing
Price: 53.0 GBP
Availability: InStock

Medical & Healthcare Practitioners

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Description

The present study includes the Formulation and Evaluation of Mucoadhesive Buccal Patch of Timolol Maleate for this study work timolol maleate selected as model drug and using either ionic polymers (SCMC) or non-ionic polymers (carbopol, HPMC).The fabricated patches were prepared by solvent casting method. The mean thicknesses of the buccal patch formulations were 0.34 – 0.43 mm.Moisture uptake of transdermal patches were found to be 2.94-4.13.which prevents the patches from microbial growth and bulkiness. As amount of PVP increased in every polymer blend, tensile strength and elongation at break were increased. Addition of PVP predominantly decreased the swelling characteristics of the buccal patches, except for SCMC. The drug content of the prepared bioadhesive buccal patches were found in the range of 91.4 - 98.54 %.Bioadhesive strength of buccal patches in following order SCMC >Carbopol>HPMC. The release of Timolol maleate from HPMC patches was slower than SCMC and CP 934.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 6204211382
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain: Amazon UK
Release Date: 13 October 2021
Listed Since: 07 November 2021

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LAP Lambert Academic Publishing Development of Mucoadhesive Buccal Patch of Timolol Maleate

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