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LAP Lambert Academic Publishing Studies on Naturally Occurring and Synthetic Quinones: Chemistry of quinones

Name: Studies on Naturally Occurring and Synthetic Quinones: Chemistry of quinones
Brand: LAP Lambert Academic Publishing
Price: 64.0 GBP
Availability: InStock

Chemistry

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Description

Many synthetic as well as natural products containing the quinone functionality have displayed useful chemotherapeutic activity. Benzoyl/naphthoyl/thienoyl-1,4-benzoquinones have emerged as potential building blocks for the synthesis of medicinally significant anthracyclinones. Anthracyclinones are valuable drugs in the treatment of certain human cancers. The 1,4-benzoquinones are strong electrophiles in the Diels-Alder reactions with variously substituted 1,3-butadienes. This property of quinones has been of great synthetic value.Encouraged by remarkable achievements in the field of naturally occurring as well as synthetic quinones , a systematic study of quinones including their isolation and synthesis have been undertaken. In the present study isolation of quinones from Tecomellaundulata, synthesis of rhinacanthin-A (a naphthoquinone) from lapachol and a number of benzoyl-1,4-benzoquinones were synthesized which are good precursors for the Diels-Alder reaction with various dienes and therefore, this approach may further be extended to the synthesis of anthracyclinones.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 6202530944
Category: Books > Subjects > Science, Nature & Maths > Chemistry
Domain: Amazon UK
Release Date: 29 April 2020
Listed Since: 16 May 2020

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LAP Lambert Academic Publishing Studies on Naturally Occurring and Synthetic Quinones: Chemistry of quinones

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LAP Lambert Academic Publishing Studies on Naturally Occurring and Synthetic Quinones: Chemistry of quinones

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