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LAP Lambert Academic Publishing Tissue is the issue: Endobronchial Ultrasonography and EBUS-TBNA

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Description
Direct real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) using the convex probe endobronchial ultrasound (CP-EBUS) is a relatively new minimally-invasive and accurate technique for preoperative staging of NSCLC patients. Tissues obtained by EBUS-TBNA allow further analyses to be carried out and may help directing NSCLC patients to molecularely-based different therapies. The objective for this work was to investigate the feasibility of EBUS-TBNA for obtaining nodal tissue samples that can be utilized for IHC analysis. Patients with pN2-NSCLC were enrolled. Mediastinal LN specimens obtained by EBUS-TBNA in those patients underwent IHC staining for the expression of 6 cell cycle-related proteins (pRb, cyclin D1, p16, p53, p21, and Ki-67). Results revealed that immunohistochemical staining was feasible in all mediastinal nodal tissue samples. All the examined cases showed an abnormal expression of at least one of the studied 6 cell cycle proteins. In conclusion, EBUS-TBNA is an effective tool, not only for staging of LC, but also for obtaining mediastinal nodal tissue samples amenable for further evaluation.

Product Specifications
Brand
LAP Lambert Academic Publishing
Format
paperback
ASIN
6139902630
Category
Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners
Domain
Amazon UK
Release Date
16 August 2018
Listed Since
12 September 2018

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No barcode data available

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