Polímeros biocompatibles en la quimioterapia contra la leishmaniasis: Microcápsulas de ácido poli (láctico-co-glicólico) como sistema de liberación prolongada de fármacos leishmanicidas - Image 1

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EAE Editorial Academia Espanola Polímeros biocompatibles en la quimioterapia contra la leishmaniasis: Microcápsulas de ácido poli (láctico-co-glicólico) como sistema de liberación prolongada de fármacos leishmanicidas

Name: Polimeros biocompatibles en la quimioterapia contra la leishmaniasis: Microcapsulas de acido poli (lactico-co-glicolico) como sistema de liberacion prolongada de farmacos leishmanicidas
Brand: EAE Editorial Academia Espanola
Price: 49.0 GBP
Availability: InStock

35173488

Organic Chemistry

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Description

La leishmaniasis cutánea es una enfermedad parasitaria tropical caracterizada por el surgimiento de lesiones dérmicas como foco de la infección, y ha sido reconocida en varios países como un problema de salud pública. Teniendo en cuenta la ineficacia, las múltiples dosis requeridas y los numerosos efectos secundarios que acarrean los fármacos leishmanicidias usados en la quimioterapia actual, este trabajo plantea el empleo de dispositivos de liberación controlada de sustancias para coadyuvar al aumento de la especificidad de acción y la disminución de la cantidad y frecuencia de dosificación de dichas drogas mediante la administración localizada y constante de éstas de manera tópica, comprendiendo además la experimentación con ciclopirox olamina, un antifúngico comercial de baja toxicidad cuya actividad parasiticida ha venido siendo avistada. El dispositivo de liberación controlada consistió en microcápsulas preparadas a partir de ácido poli (láctico-co-glicólico) (abreviado como PLGA), un copolímero biocompatible, biodegradable y vulnerable en ambientes acuosos (y, por ende, fisiológicos) que ha sido objeto de extensos estudios y utilización en estas aplicaciones biomédicas.

Product Specifications

Brand: EAE Editorial Academia Espanola
Model: 35173488
Format: paperback
ASIN: 6139009561
Category: Books > Subjects > Science, Nature & Maths > Chemistry > Organic Chemistry
Domain: Amazon UK
Release Date: 08 December 2018
Listed Since: 03 January 2019

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EAE Editorial Academia Espanola Polímeros biocompatibles en la quimioterapia contra la leishmaniasis: Microcápsulas de ácido poli (láctico-co-glicólico) como sistema de liberación prolongada de fármacos leishmanicidas

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