Springer Intensity-Modulated Radiation Therapy: Clinical Evidence and Techniques

Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist. Review “The book is well written and illustrated and each chapter is extensively referenced. The strength of the book is the breadth of its content which lends it to readers looking to have an overview of the subject and will therefore be suited to radiation oncology trainees, therapeutic radiographers and trainee physicists. … The addition of this book to the current stock in the libraries of radiation oncology facilities where training is undertaken should be considered.” (Dr. John Logue, RAD Magazine, December, 2015) “The book covers foundations and techniques for IMRT. It has the added benefit of including emerging technologies such as adaptive radiation therapy (ART) and the use of molecular imaging techniques for preferential targeting of high tumor burden regions. … this would be a nice addition to the library of a medical physics or radiation oncology resident.” (Carri K. Glide-Hurst, Doody’s Book Reviews, October, 2015) From the Back Cover Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist. About the Author Yasumasa Nishimura Professor, Department of Radiation Oncology, Kinki University School of Medicine Ritsuko Komaki Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston.