Parameter Identification Techniques for Systems Biology Models: Gradient Approximation and Optimization Methods - Image 1

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LAP Lambert Academic Publishing Parameter Identification Techniques for Systems Biology Models: Gradient Approximation and Optimization Methods

Name: Parameter Identification Techniques for Systems Biology Models: Gradient Approximation and Optimization Methods
Brand: LAP Lambert Academic Publishing
Price: 55.0 GBP
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Biological Science

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Mathematical models for revealing the dynamics and interaction properties inside biological systems play an important role in computational systems biology. This work is motivated by the current difficulties in identifying practical bio-system models. In the field of systems biology, available data are often noisy, sparse and expensive to collect. Therefore, system identification is a challenging problem. A major task of identifying a model, as described in terms of non-linear ordinary differential equations (ODEs) with indeterminate parameters, can be formulated into an optimization problem. It is a reverse engineering exercise to reconstruct the system model via various numerical tools like constraint-mixed-optimization algorithms and approximations. Due to sensitivity issues, in many cases, even the simulated output data, as generated by the identified model with a set of estimated parameters, fit very well with the measured data, it is still important to infer how well these model parameters being determined; which is essential for the investigation of model construction. For this reason, the identifiability issues, which is an important practical issue, is also treated.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 3846533653
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 15 June 2012
Listed Since: 19 June 2012

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LAP Lambert Academic Publishing Parameter Identification Techniques for Systems Biology Models: Gradient Approximation and Optimization Methods

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It has never been this cheap. We have no record of a lower price.

LAP Lambert Academic Publishing Parameter Identification Techniques for Systems Biology Models: Gradient Approximation and Optimization Methods

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