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EAE Editorial Academia Espanola Análisis del perfil de expresión génico hepático hormono-dependiente: Aplicación de la tecnología de DNA microarrays

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Description

La tecnología de DNA microarrays ha supuesto una revolución en el campo de la genómica, permitiendo una rápida adquisición de conocimientos. La generación de hipótesis basadas en información procedente de este tipo de metodologías está permitiendo acelerar el descubrimiento de nuevos mecanismos de acción hormonales relevantes. Esto está siendo especialmente útil en el acmpo de la endocrinología, fundamentalmente debido a que la regulación de la expresión de determinados genes es un mecanismo clave por el cual las hormonas ejercen sus acciones en el organismo. En esta Tesis Doctoral se ha empleado esta tecnología con el propósito de caracterizar la respuesta del hígado a las acciones de los estrógenos, la hormona de crecimiento y las hormonas tiroideas. La presente Tesis Doctoral fue dirigida por el profesor Dr. Leandro Fernández Pérez de la Universidad de Las Palmas de Gran Canaria, y realizada en colaboración con el Dr. Gunnar Norstedt y el Dr. Amílcar Flores Morales en el Center for Molecular Medicine del Instituto Karolinska (Estocolmo, Suecia).

Product Specifications

Format
paperback
Domain
Amazon UK
Publication Date
13 September 2011
Listed Since
26 September 2011

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