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UNIV EUROPEENNE Détection d'événements chimiques et biologiques sur nanostructures: Détection directe d'événements chimiques et biologiques en milieu liquide sur nanostructures de silicium

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Description

Les laboratoires sur puces sont une des voies en cours d’exploration pour répondre à un besoin croissant d’analyses automatiques, miniaturisées, portables et rapides. Le mode de détection basé sur l’utilisation d’un EOSFET (Electrolyte-Oxide-Semiconductor Field Effect Transistor ou Transistor à Effet de Champ Electrolyte-Oxyde-Semiconducteur), permet une détection directe de l’interaction biologique par effet de champ et semble particulièrement prometteur, notamment lorsque la taille des dispositifs est réduite à une échelle nanométrique. Notre travail porte ainsi sur l’étude de dispositifs EOSFET dont le canal est une nanostructure unidimensionnelle. Nous mettons tout d’abord en oeuvre la conception et la fabrication des dispositifs et réalisons leurs caractérisations à l'aide d'un banc de mesure dédié. Nous développons ensuite deux voies de fonctionnalisation des EOSFET, l’une permettant la détection d’une variation de pH de la solution, l’autre la présence de brins d’ADN cibles dans la solution. Le fonctionnement du dispositif dans différentes conditions permet de mettre en évidence plusieurs paramètres clés à maîtriser pour réaliser une détection électrique sur EOSFET.

Product Specifications

Format
paperback
Domain
Amazon UK
Release Date
05 November 2012
Listed Since
21 February 2013

Barcode

No barcode data available

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