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Price distribution over 47 days • 1 price levels

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Most common price: £68 (47 days, 100.0%)

Price range: £68 - £68

Price levels: 1 different prices over 47 days

Description

In general, infection of a host by multiple pathogens has important clinical implications. In conjunction with HIV, co-infections are associated with a significantly decreased survival probability. Unexpectedly, long-term viremia of the apathogenic GB Virus C (GBV-C) leads to improved survival of GBV-C co-infected HIV patients. However, epidemiological studies cannot prove a causal relationship nor they distinguish whether the observed reduction in HIV associated morbidity and mortality is caused by GBV-C/HIV interference or if GBV-C serves just as a surrogate marker for a robust immune system. Therefore, cell culture experiments were necessary. Indeed, GBV-C inhibits different HIV strains and clades. The underlaying mechanism of HIV suppression is complex. In addition to GBV-C proteins, such as the E2 glycoprotein that possess the ability to inhibit HIV entry or the NS5A protein that may imair later HIV replication steps, GBV-C elicits antibodies that neutralize HIV comparable to the broad reactive human anti-gp41 antibodies 2F5 and 4E10, as well. Taken together a combination of both inhibitory effects present an innovative approach for further drug development and vaccine design.

Product Specifications

Brand: Südwestdeutscher Verlag für Hochschulschriften
Format: paperback
ASIN: 3838123832
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Release Date: 01 February 2011
Listed Since: 09 March 2011

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Südwestdeutscher Verlag für Hochschulschriften Viral Interference of GB Virus C and Human Immunodeficiency Viruses: Different GB Virus C Proteins interfere with the Replication of HIV-1

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It has never been this cheap. We have no record of a lower price.

Südwestdeutscher Verlag für Hochschulschriften Viral Interference of GB Virus C and Human Immunodeficiency Viruses: Different GB Virus C Proteins interfere with the Replication of HIV-1

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

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