New Therapeutic Targets in Rheumatoid Arthritis (Progress in Inflammation Research) - Image 1

£188.50

Birkhauser New Therapeutic Targets in Rheumatoid Arthritis (Progress in Inflammation Research)

Name: New Therapeutic Targets in Rheumatoid Arthritis (Progress in Inflammation Research)
Brand: Birkhauser
Price: 188.5 GBP
Availability: InStock

Diseases & Disorders

This is the most expensive it has ever been. Walk away.

£189 today · previous high £189 · all-time low £137

NEW HERE?

Amazon shows you one price. We show you all of them.

Tosheroon watches Amazon prices so you don't have to. Every product on Amazon has a price history — we make it visible. Set the price you'd actually pay, and we'll email you the second it gets there. No app, no account, one email.

WHAT'S ON THIS PAGE

↓ Price chart
when this has been cheap or pricey

↓ Forecast
where the price is heading next

↓ Statistics
all-time high & low, recent range

↑ Price alert
name your number, we'll email you

Price History & Forecast

Grey patches = out of stock. Cheaper = lower on the chart. Hover for exact prices.

Last 71 days · 71 data points (no recent data)

Historical

Generating forecast…

Price Distribution

Price distribution over 71 days • 3 price levels

Days at Price

Current Price

Price Analysis

Most common price: £189 (50 days, 70.4%)

Price range: £137 - £189

Price levels: 3 different prices over 71 days

Description

During the past decades important breakthroughs have been made in the treatment of rheumatoid arthritis (RA). First, the implementation of low-dose methotrexate and other conventional disease-modifying anti-rheumatic drugs was introduced as an effective treatment. Second, it was recognized that early immunomodu- tory treatment is crucial for controlling the disease and its long-term destructive effects more effectively. Parallel advances in research on the pathogenesis of RA and cytokine biology converged in identifying tumor necrosis factor (TNF) as a key factor in inflammation and matrix destruction. The concept arose that elevated TNF concentrations at the sites of inflammation were driving disease pathology, and the removal of excess TNF from sites of inflammation became a therapeutic goal. Clearly, TNF blockade has revolutionized the treatment of RA, as well as other immune-mediated inflammatory diseases. Anti-TNF treatment results in cli- cal benefit in a significant proportion of the patients, and it has provided proof of concept for the principle of targeted therapy. Despite the impressive disease-modifying effects of the TNF blockers, not all patients respond, and patients who exhibited an initial response may lose response due to the development of anti-drug antibodies (human anti-chimeric antibodies and human anti-human antibodies, respectively) and perhaps as a result of escape mechanisms related to the disease process. In fact, the majority of the patients still have disease activity in at least one or two actively inflamed joints.

Product Specifications

Brand: Birkhauser
Format: hardcover
ASIN: 3764382376
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Internal Medicine > Diseases & Disorders
Domain: Amazon UK
Release Date: 13 March 2009
Listed Since: 03 September 2007

Barcode

No barcode data available

Birkhauser New Therapeutic Targets in Rheumatoid Arthritis (Progress in Inflammation Research)

This is the most expensive it has ever been. Walk away.

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

Similar Products You Might Like

The Handbook of Biological Therapy

Biologics in Rheumatology: New Developments, Clinical Uses & Health Implication

Rheumatology, An Issue of Medical Clinics of North America: Volume 105-2 (The Clinics: Internal Medicine, Volume 105-2)

Arthritis: Models and Mechanisms

Inflammatory Diseases and Copper: The Metabolic and Therapeutic Roles of Copper and Other Essential Metalloelements in Humans: 2 (Experimental Biology and Medicine, 2)

Advances in TNF Family Research: Proceedings of the 12th International TNF Conference, 2009: 691 (Advances in Experimental Medicine and Biology, 691)

Principles of Clinical Rheumatology

Inflammatory Diseases and Copper: The Metabolic and Therapeutic Roles of Copper and Other Essential Metalloelements in Humans: 2 (Experimental Biology and Medicine, 2)

Oxford Textbook of Psoriatic Arthritis (Oxford Textbooks in Rheumatology)

Oxford Textbook of Rheumatology

Advances in TNF Family Research: Proceedings of the 12th International TNF Conference, 2009: 691 (Advances in Experimental Medicine and Biology, 691)

Clinical Innovation in Rheumatology: Past, Present, and Future

Addressing Unmet Medical Needs in Rheumatoid Arthritis

Textbook of Pediatric Rheumatology

Tumor Necrosis Factor (Cell Biology Research Progress)

Tumor Necrosis Factor: Methods and Protocols: 98 (Methods in Molecular Medicine, 98)

Oxford Textbook of Rheumatoid Arthritis - Oxford University Press

Rheumatology, 2-Volume Set

Health Disparities in Rheumatic Diseases: Part I, An Issue of Rheumatic Disease Clinics of North America: Volume 46-4 (The Clinics: Internal Medicine, Volume 46-4)

Clinical Trials in Rheumatoid Arthritis and Osteoarthritis

Elsevier Rheumatology Secrets, 4th Edition - Medical Review

Firestein & Kelley's Textbook of Rheumatology, 2-Volume Set

Unique or Select Procedures, An Issue of Orthopedic Clinics (Volume 50-3) (The Clinics: Orthopedics, Volume 50-3)

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases: Pathophysiology, Clinical Aspects and Therapeutic Approaches