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Price Distribution

Price distribution over 41 days • 1 price levels

Days at Price

Price Analysis

Most common price: £92 (41 days, 100.0%)

Price range: £92 - £92

Price levels: 1 different prices over 41 days

Description

Over the past 30 years, astrocytes have emerged from a supporting role to co-starring with neurons and oligodendrocytes as players in CNS disorders. Dysfunction of astrocytes is now implicated in disorders once thought to be solely of neuronal origin, such as epilepsy, amyotrophic lateral sclerosis, and depression. It is also implicated in disorders previously ascribed solely to oligodendrocytes, like multiple sclerosis, vanishing white matter disease, and megalencephalic leukoencephalopathy with subcortical cysts. In some instances, the disease cause is a defect originating in astrocytes. The first and perhaps most definitive example is Alexander disease, in which coding mutations in the GFAP gene can cause massive dysmyelination and perturb multiple neuronal circuits. In other instances, induced disruption of normal astrocyte functions, such as glutamate or potassium transport, exacerbates the disease process. The purpose of this Special Issue is to illustrate the broad-ranging involvement of astrocytes in CNS disorders. Understanding their role in a variety of CNS disorders will be informative both for revealing normal interactions between astrocytes and other CNS cell types, and for identifying therapeutic targets.

Product Specifications

Format: hardcover
ASIN: 3725822972
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain: Amazon UK
Release Date: 04 November 2024
Listed Since: 05 December 2024

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Astrocytes in CNS Disorders

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Astrocytes in CNS Disorders

Price History & Forecast

Price Distribution

Price Analysis

Description

Product Specifications

Barcode

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