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Porcine Models of Neurotrauma and Neurological Disorders

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Last 34 days · 34 data points (no recent data)

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£68.60 £68.37 £68.42 £68.47 £68.52 £68.57 £68.62 12 August 2026 20 August 2026 28 August 2026 05 September 2026 14 September 2026
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Price distribution over 34 days • 1 price levels

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34 days 0 9 17 26 34 £69 Days at Price

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Price range: £69 - £69

Price levels: 1 different prices over 34 days

Description
The translation of therapeutics from the lab to the clinic has a dismal record in the fields of neurotrauma and neurological disorders. This is due, in part, to the challenging heterogeneity of the clinical population common to all translational research, but it is also due to the unique challenges of recreating the mechanisms and manifestations of human neurological injury/disorders in small animals. Large animal models are an essential component of successful pipelines for moving discoveries from bench to bedside in other fields (e.g., exploring device or therapeutic scale-up and/or IND/IDE enabling studies), and neuroscience has made significant progress toward establishing such pipelines in its many unique subfields. Due to their size, gyrencephalic brains, high white matter content, and other factors, swine have proven to be ideal for providing high-fidelity, clinically relevant studies to bridge the gap between small animals and humans. Only by recognizing the strengths and limitations of our models can we hope to effectively develop, validate, and translate novel neuroprotective and regenerative therapeutics into clinical practice, in order to maximize functional recovery. Herein, we provide detailed descriptions of and findings from some of the sophisticated swine model systems that have been developed to empower translational research in neurotrauma and neurological disorders.

Product Specifications
Format
hardcover
ASIN
3725805059
Category
Books > Subjects > Science, Nature & Maths > Biological Sciences > Biological Science
Domain
Amazon UK
Release Date
07 May 2024
Listed Since
08 May 2024

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No barcode data available

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