Modelirovanie trekhmernogo opiatnogo farmakofora: Teoreticheskie i prikladnye aspekty - Image 1

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Palmarium Academic Publishing Modelirovanie trekhmernogo opiatnogo farmakofora: Teoreticheskie i prikladnye aspekty

Name: Modelirovanie trekhmernogo opiatnogo farmakofora: Teoreticheskie i prikladnye aspekty
Brand: Palmarium Academic Publishing
Price: 68.0 GBP
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Biochemistry

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Kniga posvyashchena probleme teoreticheskoy otsenki svoystv ligandov opiatnykh retseptorov v ramkakh kontseptsii farmakofora. Pokazana evolyutsiya ponyatiya «farmakofor» s izmeneniem predstavleniy o prichinakh bioaktivnosti soedineniy, otrazhena sovremennaya tochka zreniya na mekhanizm aktivatsii opiatnykh retseptorov, baziruyushchayasya na rezul'tatakh khimernogo i sayt-napravlennogo mutageneza klonirovannykh opiatnykh retseptorov, komp'yuternogo modelirovaniya zony retseptsii i ligand-retseptornykh kompleksov. Avtorom opisany izvestnye trekhmernye modeli opiatnogo farmakofora, razrabotannye s ispol'zovaniem traditsionnoy metodologii i metodom sravnitel'nogo analiza molekulyarnykh poley, a takzhe predlozhena sobstvennaya model', sozdannaya s pomoshch'yu al'ternativnoy strategii poiska strukturnogo podobiya molekul na osnove obobshcheniya i analiza eksperimental'nykh dannykh poslednikh desyatiletiy. Teoreticheskie i prikladnye aspekty formirovaniya universal'noy trekhmernoy modeli opiatnogo farmakofora rassmatrivayutsya avtorom v ramkakh predstavleniy supramolekulyarnoy khimii. Kniga predstavlyaet interes dlya shirokogo kruga spetsialistov v oblasti khimii i biokhimii, interesuyushchikhsya voprosami komp'yuternogo molekulyarnogo modelirovaniya.

Product Specifications

Brand: Palmarium Academic Publishing
Format: paperback
ASIN: 3659983721
Category: Books > Subjects > Science, Nature & Maths > Biological Sciences > Biochemistry
Domain: Amazon UK
Release Date: 24 February 2013
Listed Since: 05 March 2013

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Palmarium Academic Publishing Modelirovanie trekhmernogo opiatnogo farmakofora: Teoreticheskie i prikladnye aspekty

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Palmarium Academic Publishing Modelirovanie trekhmernogo opiatnogo farmakofora: Teoreticheskie i prikladnye aspekty

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