Development of Mouth Dissolving Tablets: Prednisolone Mouth Dissolving Tablets - Image 1

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LAP Lambert Academic Publishing Development of Mouth Dissolving Tablets: Prednisolone Mouth Dissolving Tablets

Name: Development of Mouth Dissolving Tablets: Prednisolone Mouth Dissolving Tablets
Brand: LAP Lambert Academic Publishing
Price: 50.0 GBP
Availability: InStock

Pharmacology

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Description

Prednisolone is a glucocorticoid with the general properties of the corticosteroids. It is used as anti-inflammatory or immunosuppressive agent in asthmatic condition mostly in pediatric and geriatric population. So the present investigation was conducted with an aim of to formulate a taste masked patient friendly dosage form. i.e. mouth dissolving tablets of prednisolone. In this study, taste masking of drug was critical parameter for this study. Masking of bitter taste of prednisolone was carried out using techniques like preparation of solid dispersion with PEG 6000, complex formation with Indion-204 resin and β-cyclodextrin. Among them complex prepared from β-cyclodextrin in weight ratio 1:4 was optimized basis on taste panel evaluation and drug release from complex. A successful taste masking of complex was confirmed by time intensity method and also by taking drug release in simulated gastric fluid and in simulated salivary fluid.

Product Specifications

Brand: LAP Lambert Academic Publishing
Format: paperback
ASIN: 365988748X
Category: Books > Subjects > Health, Family & Lifestyle > Medical & Healthcare Practitioners > Other Branches of Medicine > Pharmacology
Domain: Amazon UK
Release Date: 13 May 2016
Listed Since: 06 June 2016

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LAP Lambert Academic Publishing Development of Mouth Dissolving Tablets: Prednisolone Mouth Dissolving Tablets

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